Characterizing Cefepime Neurotoxicity: A Systemic Review
نویسندگان
چکیده
منابع مشابه
Characterizing Cefepime Neurotoxicity: A Systematic Review
Neurotoxicity due to cefepime has not been well characterized. We performed a systematic review of the literature and included 5 additional cases from our center. Of the 198 cases found, the mean age was 67 years and 87% of patients had renal dysfunction. The most common clinical features were diminished level of consciousness (80%), disorientation/agitation (47%), and myoclonus (40%). It is wo...
متن کاملCefepime Neurotoxicity in Patients with Renal Insufficiency
Cefepime is a fourth-generation cephalosporin that is active against both gram-positive and gram-negative organisms. It is administered parenterally for the treatment of severe infections. Approximately 85% of the drug is excreted unchanged by the kidneys. Neurotoxicity in patients with renal failure who are treated with cefepime has been reported sporadically. We report on two senile patients ...
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We present here a case of 58-year-old male operated for coronary artery bypass graft surgery with four grafts. He developed neurologic symptoms with injection cefepime which recovered after withdrawal of the drug.
متن کاملCefepime induced neurotoxicity: A case series and review of the literature
Cefepime is a fourth generation cephalosporin which is bactericidal for broad spectrum of organisms. This is a case-series of three patients who presented to our hospital with confusion secondary to cefepime use to treat urinary tract infection (UTI) and health care associated pneumonia (HCAP), after excluding other common etiologies of altered mental status (AMS). Of these three patients, one ...
متن کاملCefepime‐induced neurotoxicity in a pediatric patient on chronic hemodialysis: a case report
Impaired renal function increases the risk for cefepime-induced neurotoxicity. Symptoms include disorientation, myoclonus, status epilepticus, ataxia, gait disturbance, coma, and death. A high index of suspicion and early recognition of symptoms can minimize the risk of progression of symptoms to permanent neurologic impairment or death.
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2016
ISSN: 2328-8957
DOI: 10.1093/ofid/ofw172.1348